Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.5
Supplement Facts
Serving Size: 4 capsules
Amount Per Serving
%DV
Vitamin D (as ergocalciferol)
10 mcg (400 I.U.)
50%
Calcium (as calcium hydroxyapatite, calcium citrate, calcium aspartate)†
1,000 mg
77%
Phosphorus (as calcium hydroxyapatite)†
500 mg
40%
Magnesium (as magnesium oxide, magnesium aspartate, magnesium citrate, magnesium taurinate)†
500 mg
119%
Top Medical Research Studies
9.5
We examined how vitamin D supplementation could help improve symptoms for those suffering from irritable bowel syndrome (IBS). This systematic review pulled together findings from four randomized, placebo-controlled trials, with a total of 335 participants, to determine the effectiveness of vitamin D on various IBS measures.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Read More
9
We aimed to find out how vitamin D supplementation might help those suffering from irritable bowel syndrome (IBS). To do this, we conducted a thorough review of nine randomized controlled trials that included a total of 780 participants.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Read More
8
We set out to investigate how vitamin D levels, particularly serum 25-hydroxyvitamin D, might affect the risk of developing irritable bowel syndrome (IBS). Using a sophisticated approach called Mendelian randomization, we analyzed data collected from large biobanks. This method allows us to draw more robust conclusions about causality, especially given the controversies surrounding previous observational studies.
Our analysis focused on a substantial number of participants and examined the genetic factors associated with both vitamin D levels and IBS. While we found no significant causal relationship between vitamin D intake and IBS, we discovered an intriguing result regarding 25-hydroxyvitamin D. Specifically, higher levels of this form of vitamin D seemed to correlate with a decreased risk of IBS. More precisely, each additional standard deviation increase in genetically determined 25-hydroxyvitamin D was linked to a 16.8% lower risk of developing IBS.
Nevertheless, it's important to acknowledge the complexity of these findings. Although we observed a negative causal relationship between 25-hydroxyvitamin D and IBS, the same could not be said for vitamin D intake or functional dyspepsia (FD). This study brushes against the broader conversation about the potential health benefits of vitamin D while acknowledging that further research is necessary to fully understand these dynamics.
Our analysis focused on a substantial number of participants and examined the genetic factors associated with both vitamin D levels and IBS. While we found no significant causal relationship between vitamin D intake and IBS, we discovered an intriguing result regarding 25-hydroxyvitamin D. Specifically, higher levels of this form of vitamin D seemed to correlate with a decreased risk of IBS. More precisely, each additional standard deviation increase in genetically determined 25-hydroxyvitamin D was linked to a 16.8% lower risk of developing IBS.
Nevertheless, it's important to acknowledge the complexity of these findings. Although we observed a negative causal relationship between 25-hydroxyvitamin D and IBS, the same could not be said for vitamin D intake or functional dyspepsia (FD). This study brushes against the broader conversation about the potential health benefits of vitamin D while acknowledging that further research is necessary to fully understand these dynamics.
Read More
Most Useful Reviews
9
Better sleep overall
Excellent product! Taking four tablets every night before bed helps me achieve better sleep, and the magnesium aids my bowel movements.
Read More
9
Convenient and effective
I purchased it for the first time and appreciate that it combines Calcium, Magnesium, and Vitamin D in one. It's very convenient! I'm highly satisfied as it supports my sleep well and addresses my magnesium deficiency, which significantly aids my bowel movements.
Read More
7.5
Enhanced bowel movements
Initially feeling empty, I found that taking it on my left side made it easier to swallow. I've noticed an improvement in my sleep quality as well as in my bowel movements!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
- All Researches
9.5
We examined how vitamin D supplementation could help improve symptoms for those suffering from irritable bowel syndrome (IBS). This systematic review pulled together findings from four randomized, placebo-controlled trials, with a total of 335 participants, to determine the effectiveness of vitamin D on various IBS measures.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Read More
9
We aimed to find out how vitamin D supplementation might help those suffering from irritable bowel syndrome (IBS). To do this, we conducted a thorough review of nine randomized controlled trials that included a total of 780 participants.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Read More
9
We conducted a study to understand how probiotic 35624 affects irritable bowel syndrome (IBS) in children and adolescents aged 8 to 18. This real-world study, carried out in Chile, involved 64 young participants over a span of 12 weeks, during which we closely monitored their gastrointestinal symptoms.
Throughout the study, participants showed significant improvements in various IBS symptoms measured by specific scoring systems. By week 6 and again at week 12, we saw strong positive changes with 98.3% of them experiencing improvements in three or more IBS domains. This shift was impressive, as the severity of their IBS symptoms moved from moderate or severe to mild or in remission.
Interestingly, the study also looked into vitamin D levels, as vitamin D deficiency is prevalent among children in Latin America. However, we found that low baseline serum vitamin D levels did not correlate with the severity of IBS symptoms or the response to the probiotic treatment. While the improvements were promising, they did not last after a two-week washout period, highlighting the need for more research to understand these effects fully, particularly regarding vitamin D's influence.
Throughout the study, participants showed significant improvements in various IBS symptoms measured by specific scoring systems. By week 6 and again at week 12, we saw strong positive changes with 98.3% of them experiencing improvements in three or more IBS domains. This shift was impressive, as the severity of their IBS symptoms moved from moderate or severe to mild or in remission.
Interestingly, the study also looked into vitamin D levels, as vitamin D deficiency is prevalent among children in Latin America. However, we found that low baseline serum vitamin D levels did not correlate with the severity of IBS symptoms or the response to the probiotic treatment. While the improvements were promising, they did not last after a two-week washout period, highlighting the need for more research to understand these effects fully, particularly regarding vitamin D's influence.
Read More
9
We investigated the impacts of a combination treatment involving probiotics and vitamin D on individuals with irritable bowel syndrome (IBS), specifically those experiencing diarrhea-predominant IBS (IBS-D) or mixed bowel movements (IBS-M). The study involved 246 adults followed by private gastroenterologists, who were given a daily dose of probiotics along with vitamin D over a period of 42 days.
At the end of this timeframe, we found that a significant number of patients—about 62.9%—reported improvements in their symptoms. In fact, there was a notable decrease in the IBS Severity Scoring System scores. This improvement also correlated with enhancements in overall quality of life related to IBS, as well as reductions in anxiety and depression symptoms.
Our findings align with earlier randomized clinical trials, reinforcing the notion that the probiotic and vitamin D combination can be beneficial. While we recognize that this study consolidates the evidence of such a combination rather than isolating the effects of vitamin D alone, the results suggest that including vitamin D in treatment plans may indeed foster better mental and gut health for those suffering from IBS.
At the end of this timeframe, we found that a significant number of patients—about 62.9%—reported improvements in their symptoms. In fact, there was a notable decrease in the IBS Severity Scoring System scores. This improvement also correlated with enhancements in overall quality of life related to IBS, as well as reductions in anxiety and depression symptoms.
Our findings align with earlier randomized clinical trials, reinforcing the notion that the probiotic and vitamin D combination can be beneficial. While we recognize that this study consolidates the evidence of such a combination rather than isolating the effects of vitamin D alone, the results suggest that including vitamin D in treatment plans may indeed foster better mental and gut health for those suffering from IBS.
Read More
9
We aimed to understand how vitamin D treatment affects individuals with irritable bowel syndrome (IBS) who didn’t have any identifiable stressors contributing to their symptoms. For this study, we provided vitamin D supplements to patients over a three-month period. Of the patients, 97 had their vitamin D levels checked again, showing sufficient improvement, while 14 were lost to follow-up.
Our approach suggested that intramuscular injections were the best form of treatment, but interestingly, we found that 34 of the participants opted for oral supplements. Those taking oral vitamin D displayed a lesser increase in serum vitamin D levels compared to those receiving injections.
The results were promising: over half, specifically 56.7%, reported complete relief from their IBS symptoms after vitamin D replacement. Additionally, 36.1% experienced significant improvement, and 6.2% noted moderate relief. The study also highlighted that even though many found relief, we need to consider the 14 individuals lost to follow-up when interpreting the overall effectiveness.
Our approach suggested that intramuscular injections were the best form of treatment, but interestingly, we found that 34 of the participants opted for oral supplements. Those taking oral vitamin D displayed a lesser increase in serum vitamin D levels compared to those receiving injections.
The results were promising: over half, specifically 56.7%, reported complete relief from their IBS symptoms after vitamin D replacement. Additionally, 36.1% experienced significant improvement, and 6.2% noted moderate relief. The study also highlighted that even though many found relief, we need to consider the 14 individuals lost to follow-up when interpreting the overall effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Better sleep overall
Excellent product! Taking four tablets every night before bed helps me achieve better sleep, and the magnesium aids my bowel movements.
Read More
9
Convenient and effective
I purchased it for the first time and appreciate that it combines Calcium, Magnesium, and Vitamin D in one. It's very convenient! I'm highly satisfied as it supports my sleep well and addresses my magnesium deficiency, which significantly aids my bowel movements.
Read More
7.5
Enhanced bowel movements
Initially feeling empty, I found that taking it on my left side made it easier to swallow. I've noticed an improvement in my sleep quality as well as in my bowel movements!
Read More
Frequently Asked Questions
9
Better sleep overall
Excellent product! Taking four tablets every night before bed helps me achieve better sleep, and the magnesium aids my bowel movements.
9
Convenient and effective
I purchased it for the first time and appreciate that it combines Calcium, Magnesium, and Vitamin D in one. It's very convenient! I'm highly satisfied as it supports my sleep well and addresses my magnesium deficiency, which significantly aids my bowel movements.
7.5
Enhanced bowel movements
Initially feeling empty, I found that taking it on my left side made it easier to swallow. I've noticed an improvement in my sleep quality as well as in my bowel movements!
9
We aimed to find out how vitamin D supplementation might help those suffering from irritable bowel syndrome (IBS). To do this, we conducted a thorough review of nine randomized controlled trials that included a total of 780 participants.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
7
Vitamin D may enhance IBS outcomes
We sought to understand whether vitamin D intake and status could help alleviate symptoms and improve the quality of life for adults suffering from irritable bowel syndrome (IBS). Our investigation involved a systematic review and meta-analysis of various studies, including clinical trials and observational studies that looked at vitamin D's effects on IBS-related outcomes.
After analyzing the data, we found moderate evidence suggesting that vitamin D supplementation can enhance serum vitamin D levels in adults with IBS. Notably, those individuals who began with low or deficient vitamin D status experienced improvements in their quality of life following supplementation. However, it is important to highlight that while these findings indicate potential benefits, the overall impact of vitamin D on symptom severity in IBS is still being explored, and results can vary among individuals.
In summary, vitamin D supplementation could be a promising avenue for those with IBS, particularly for those with a deficiency. It's an exciting area of research that could lead to better health outcomes for many.
After analyzing the data, we found moderate evidence suggesting that vitamin D supplementation can enhance serum vitamin D levels in adults with IBS. Notably, those individuals who began with low or deficient vitamin D status experienced improvements in their quality of life following supplementation. However, it is important to highlight that while these findings indicate potential benefits, the overall impact of vitamin D on symptom severity in IBS is still being explored, and results can vary among individuals.
In summary, vitamin D supplementation could be a promising avenue for those with IBS, particularly for those with a deficiency. It's an exciting area of research that could lead to better health outcomes for many.
4
We explored the connection between vitamin D and irritable bowel syndrome (IBS) by analyzing data from twelve clinical trials that included 1331 IBS patients. Our goal was to see how vitamin D levels might relate to IBS symptoms and whether vitamin D supplementation can make a difference.
The findings revealed something interesting: patients with IBS tend to have lower levels of vitamin D in their blood. While vitamin D supplementation did show an improvement in the quality of life for these patients, it did not significantly affect the overall severity of their IBS symptoms.
This indicates that while vitamin D deficiency is linked to IBS and supplementation can enhance daily living, it may not directly relieve the main symptoms that trouble patients. Therefore, vitamin D could be a valuable part of the conversation around managing IBS, but it should not be seen as a standalone treatment for symptom relief.
The findings revealed something interesting: patients with IBS tend to have lower levels of vitamin D in their blood. While vitamin D supplementation did show an improvement in the quality of life for these patients, it did not significantly affect the overall severity of their IBS symptoms.
This indicates that while vitamin D deficiency is linked to IBS and supplementation can enhance daily living, it may not directly relieve the main symptoms that trouble patients. Therefore, vitamin D could be a valuable part of the conversation around managing IBS, but it should not be seen as a standalone treatment for symptom relief.
5
We explored the relationship between vitamin D supplementation and its impact on individuals suffering from irritable bowel syndrome (IBS). This systematic review and meta-analysis analyzed data from six randomized controlled trials, which included a total of 616 patients.
Our findings showed no significant improvement in the overall severity of IBS symptoms, as measured by the Irritable Bowel Severity Scoring System (IBS-SSS). The difference between the vitamin D group and placebo was relatively small, suggesting that vitamin D may not be a game-changer for managing IBS symptoms.
However, we did observe a positive effect of vitamin D on the quality of life for IBS patients. When looking at the IBS quality of life (IBS-QoL) scores, there was a noticeable improvement for those taking vitamin D compared to the placebo group.
Furthermore, vitamin D supplementation significantly increased serum levels of calcifediol, indicating that the treatment was effective in raising vitamin D levels in participants. It's important to note, though, that further clinical trials are necessary to fully understand these effects and to generate findings that are widely applicable.
Our findings showed no significant improvement in the overall severity of IBS symptoms, as measured by the Irritable Bowel Severity Scoring System (IBS-SSS). The difference between the vitamin D group and placebo was relatively small, suggesting that vitamin D may not be a game-changer for managing IBS symptoms.
However, we did observe a positive effect of vitamin D on the quality of life for IBS patients. When looking at the IBS quality of life (IBS-QoL) scores, there was a noticeable improvement for those taking vitamin D compared to the placebo group.
Furthermore, vitamin D supplementation significantly increased serum levels of calcifediol, indicating that the treatment was effective in raising vitamin D levels in participants. It's important to note, though, that further clinical trials are necessary to fully understand these effects and to generate findings that are widely applicable.
8
We explored the relationship between vitamin D and irritable bowel syndrome (IBS), a common digestive condition that affects a significant number of adults. The findings suggest that vitamin D plays an important role in combating IBS symptoms through its effects on gut microbiota and immune regulation.
Vitamin D appears to improve gut health by promoting a balanced microbiome and enhancing the body's immune responses, which could potentially alleviate the inflammation often associated with IBS. With fewer side effects compared to other treatments, vitamin D supplementation shines as a promising option for those suffering from IBS.
Moving forward, we see a need for more in-depth studies, including epidemiological research and clinical trials, to better understand how vitamin D can be tailored to effectively improve IBS for patients. Additionally, investigating the specific mechanisms by which vitamin D alleviates symptoms may offer new insights into managing this complex disorder.
Vitamin D appears to improve gut health by promoting a balanced microbiome and enhancing the body's immune responses, which could potentially alleviate the inflammation often associated with IBS. With fewer side effects compared to other treatments, vitamin D supplementation shines as a promising option for those suffering from IBS.
Moving forward, we see a need for more in-depth studies, including epidemiological research and clinical trials, to better understand how vitamin D can be tailored to effectively improve IBS for patients. Additionally, investigating the specific mechanisms by which vitamin D alleviates symptoms may offer new insights into managing this complex disorder.
References
- Qi S, Zhao M, Sun Y, Boro S, Arora B, et al. Impact of vitamin D supplementation on symptom severity and quality of life in patients with irritable bowel syndrome: A meta-analysis. Adv Clin Exp Med. 2025. doi:10.17219/acem/191463
- Cara KC, Taylor SF, Alhmly HF, Wallace TC. The effects of vitamin D intake and status on symptom severity and quality-of-life in adults with irritable bowel syndrome (IBS): a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2024. doi:10.1080/10408398.2024.2400603
- Cruchet Muñoz S, Verbeke Palma S, Lera Marqués L, Espinosa Pizarro MN, Malig Mechasqui J, et al. Effects of 35624 in Children and Adolescents with Irritable Bowel Syndrome. Nutrients. 2024;16. doi:10.3390/nu16121967
- Jouët P, Altman C, Bruley DES Varannes S, Juhel C, Henri F. Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study. Minerva Gastroenterol (Torino). 2024;70:332. doi:10.23736/S2724-5985.24.03581-2
- Uberti F, Trotta F, Cavalli R, Galla R, Caldera F, et al. Enhancing Vitamin D3 Efficacy: Insights from Complexation with Cyclodextrin Nanosponges and Its Impact on Gut-Brain Axes in Physiology and IBS Syndrome. Int J Mol Sci. 2024;25. doi:10.3390/ijms25042189
- Xu S, Luo Q, He J, Chen X, Li S, et al. Causal associations of 25-hydroxyvitamin D with functional gastrointestinal disorders: a two-sample Mendelian randomization study. Genes Nutr. 2023;18:14. doi:10.1186/s12263-023-00734-1
- Kesavan C, Das A, Goyal P, Jackson CS, Strong DD, et al. Vitamin D Deficiency (VDD) and Benefits of Supplementation in Veterans with IBS-D. Diagnostics (Basel). 2023;13. doi:10.3390/diagnostics13172807
- Yan C, Hu C, Chen X, Jia X, Zhu Z, et al. Vitamin D improves irritable bowel syndrome symptoms: A meta-analysis. Heliyon. 2023;9:e16437. doi:10.1016/j.heliyon.2023.e16437
- Yu XL, Wu QQ, He LP, Zheng YF. Role of in vitamin D in irritable bowel syndrome. World J Clin Cases. 2023;11:2677. doi:10.12998/wjcc.v11.i12.2677
- Alvi H, Ali G, Iqbal S, Ahsan MN, Siddiqui MA, et al. Role of 25-hydroxyvitamin D in irritable bowel syndrome patients. J Family Med Prim Care. 2022;11:7975. doi:10.4103/jfmpc.jfmpc_1336_22
- Abdelmalak MFL, Abdelrahim DS, George Michael TMA, Abdel-Maksoud OM, Labib JMW. Vitamin D and lactoferrin attenuate stress-induced colitis in Wistar rats via enhancing AMPK expression with inhibiting mTOR-STAT3 signaling and modulating autophagy. Cell Biochem Funct. 2023;41:211. doi:10.1002/cbf.3774
- Grozić A, Coker K, Dussik CM, Sabir MS, Sabir Z, et al. Identification of putative transcriptomic biomarkers in irritable bowel syndrome (IBS): Differential gene expression and regulation of TPH1 and SERT by vitamin D. PLoS One. 2022;17:e0275683. doi:10.1371/journal.pone.0275683
- Abuelazm M, Muhammad S, Gamal M, Labieb F, Amin MA, et al. The Effect of Vitamin D Supplementation on the Severity of Symptoms and the Quality of Life in Irritable Bowel Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2022;14. doi:10.3390/nu14132618
- Bin Y, Kang L, Lili Y. Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: a systematic review and meta-analysis. Nutr Hosp. 2022;39:1144. doi:10.20960/nh.04044
- Huang H, Lu L, Chen Y, Zeng Y, Xu C. The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis. Nutr J. 2022;21:24. doi:10.1186/s12937-022-00777-x
- Chong RIH, Yaow CYL, Loh CYL, Teoh SE, Masuda Y, et al. Vitamin D supplementation for irritable bowel syndrome: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2022;37:993. doi:10.1111/jgh.15852
- Heydari P, Ghanadian M, Asghari G, Azimi M, Babaeian M, et al. A double-blind randomized clinical trial of Boiss. in the patients with diarrhea-predominant irritable bowel syndrome. Res Pharm Sci. 2023;18:89. doi:10.4103/1735-5362.363599
- Harvey RF, Read AE. Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome. Gut. 1973;14:983.
